Holiday greetings to all PES Members and Friends!
As we close out another calendar year, one naturally considers 2023’s issues and events. The year will be most remembered for our first and highly successful independent in-person meeting, mixed with those beautiful views of San Diego’s harbor. Personally, I reflect on my deep dive into society leadership and the satisfaction of working hard with a dedicated, talented, and supremely collegial Board of Directors. With many new initiatives behind us, we will continue our efforts to advocate for our mission(s) and to build successful programs in the coming year. At the top of the list is to bring our members a friendly, fresh, and intellectually stimulating 2024 annual meeting.
With the heart of these efforts in mind, I wish to highlight the Education Committee, chaired by Todd Nebesio. The committee is the largest of our standing committees and centrally engaged in many important Society activities.
Todd D. Nebesio, MD
Perhaps the most celebrated program the committee managed this year was the highly successful Discovery Program where students and first year residents received support for attending the Annual meeting. This created a great deal of enthusiasm about endocrinology at an early stage, and the program is to be expanded next year. The committee also arranges a quarterly webinar series, most recently related to an outstanding review of congenital hyperinsulinism, and has speakers engaged throughout 2024. The group is responsible for a host of educational materials, including the recent production of diabetes videos for newly diagnosed patients. Numerous educational materials, including both patient- and provider-directed handouts for endocrine diagnoses are available (and in several languages), thanks to them. Currently the work of planning the Spring Fellows’ Retreat is underway. I applaud Todd for mastering the organization of such a busy committee, as well as the various subcommittee chairs he coordinates within the larger group. Much of our mission is in their hands.
Wishing all of you the best of holidays and looking forward to a productive New Year.
Best,
Tom Carpenter, MD
Tis the Season! Is it time to renew your dues?
PES membership is on a calendar year so likely time to renew! Accessing your membership record and checking your membership status is easy!
Visit the website and check your membership status by using your PES membership credentials and logging into this link: https://pedsendo.app.neoncrm.com/login.jsp
Click the button in the top right corner labeled “Renew”. This will take you to the renewal page. Please also review your complete record and make sure the demographical information is filled out and current. This information helps us tailor program and services that best meet your needs and preferences.
For a receipt, click “Membership” on the left-hand side. Then select the membership charge you want a receipt for. Finally, click the “Download” button to download that receipt. Then you should be all set!
MAP Spotlight: Ascendis Pharma-New InsiGHTS – A New U.S. Clinical Trial for Children with Turner syndrome
New InsiGHTS is a U.S. clinical trial sponsored by Ascendis Pharma to investigate the safety, tolerability, and efficacy of lonapegsomatropin, a once-weekly injection, in children with impaired growth due to Turner syndrome, compared to once-daily injection of somatropin.
This Phase 2, dose-finding, open-label trial will compare the annualized height velocity of children with Turner syndrome receiving once-weekly lonapegsomatropin to those receiving daily somatropin. The trial is currently recruiting participants across the U.S.
Enrolled children will be randomized into one of four treatment groups to receive one of three doses of weekly lonapegsomatropin or daily somatropin.
Eligibility: Children 1 to 10 years of age diagnosed with Turner syndrome who are growth hormone treatment naive.
Participation
- Multiple medical centers across the U.S. are participating in the trial.
- For eligible patients, coordinated travel arrangements and expense reimbursements for certain trial- related costs will be provided.
- Contact Ascendis Pharma at NewInsightsTrial@Ascendispharma.com for details about the study locations and participation criteria.
For more information, please visit newinsightstrial.com or clinicaltrials.gov (NCT05690386).
About the Sponsor: Founded in 2007, Ascendis Pharma is applying its innovative TransCon™ technology platform to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients’ lives. We are headquartered in Copenhagen, Denmark, and have additional offices in Germany (Heidelberg, Munich, and Berlin) and the United States (Palo Alto and Redwood City, California, and Princeton, New Jersey). Learn more about Ascendis Pharma at www.ascendispharma.com.
Endocrine Update 2024
February 5-9, 2024
Wyndham Grand Rio Mar Puerto Rico Golf & Beach Resort – Rio Grande, Puerto Rico, or Livestream
Mayo Clinic School of Continuous Professional Development (MCSCPD) at 1-800-323-2688 / 1-507-284-2509 or cme@mayo.edu.
Online Education
Tuesday, January 16, 2024 I 03:00 pm – 5:00 pm EST
Calling all Fellows! PedsENDO365 – Career Pathways for Pediatric Endocrine Fellows
This activity addresses the following key concepts: 1. Common viable career paths after fellowship training. 2. Importance of identifying what paths match values, skills, and interests 3. Role of networking in identifying mentors and job prospects.
Learning Objectives
- Describe the career pathways available after endocrine fellowship
- Identify what career pathway/s match your skills, values, and interests.
- Evaluate two possible career paths and the next steps needed via networking with professionals at various stages of a career in that track (clinician-scientist (basic/clinical), clinician-educator, industry, private practice)
Speakers: To be confirmed
Register here: https://zoom.us/meeting/register/tJMqcuuprT4uH9AzyQZFRPBNFMr2qm_kUe0L
Friday, January 19, 2024 I 4:00 PM EST
Student Endocrinology Exposure Development (SEED) Webinar – Hypoglycemia
SEED is a novel interactive session series that aims to enhance clinical learning for medical students and increase their exposure to pediatric endocrinology. For more information on this initiative, please visit our SEED page on our website
This talk will present an overview of the differential diagnosis of hypoglycemia, digging in deeper on hyperinsulinism, the most common cause of persistent HI in infants and children.
Learning Objectives
- review the differential diagnosis of hypoglycemia
- review initial evaluation to determine cause of hypoglycemia
- review the diagnosis and management of hyperinsulinism
Speaker: Dr Winnie Sigal, Pediatric Endocrinologist, Assistant Professor of Pediatrics UPenn / CHOP
Register here: https://zoom.us/meeting/register/tJMudeyppjgoGtEoROhzdHqDRgSaXInwbhWP
Monday, January 29, 2024 I 4:00 pm – 5:00 pm EST
Quarterly Education Committee Webinar – Islet auto-transplantation in children
This talk will discuss islet cell auto-transplantation in children.
Learning Objectives
- Understand the rationale for total pancreatectomy with islet auto-transplantation
- Understand the procedure of a total pancreatectomy with islet auto-transplantation
- Be familiar with islet function outcomes after islet auto-transplantation
Speakers: Melena Bellin, MD, Professor, Pediatric Endocrinology, and Surgery, Co-Director, Total Pancreatectomy, and Islet Auto-transplant Program, Albert D. and Eva J. Corniea Chair
University of Minnesota
Register here: https://zoom.us/meeting/register/tJYqd-ihqzMuHNKhyMORkgiIjw9b8Yj2pfJV
New Paediatric Endocrinology Journal
The open access journal, Children, has incorporated a new section devoted to Pediatric Endocrinology, which will be edited by Zvi Laron. The scope of this venue will include original articles and reviews, and yet another option for the dissemination of exciting work in our field. More information is available at: https://www.mdpi.com/journal/children
Congratulations to Zvi for his work in moving this forward!
News From the NIH-You Are Invited To Participate in a Pilot of Data Management and Sharing Plan Templates
By Mike Lauer
Since March, we have engaged with the Federal Demonstration Partnership to pilot test two data management and sharing (DMS) plan templates. These templates were developed in close collaboration with staff and leadership from offices across NIH, and we seek your input on them.
Case Study in Research Integrity: This Application Feels Familiar
By Mike Lauer
In this case study, we will discuss how plagiarism in the grant application process is handled at NIH and remind the research community about the importance of maintaining confidentiality of the peer review process.
Read More: Case Study in Research Integrity: This Application Feels Familiar – NIH Extramural Nexus
EDI Spotlight: Diabetes Technology Equity
Meet Sarah Allan, MD, University of Alabama at Birmingham
Equity, Diversity and Inclusion Initiative – Pediatric Endocrine Society (pedsendo.org)
Fellow Spotlight: Fulfilled Ighalo, MD
Meet Fulfilled: December Fellow Spotlight – Fulfilled Ighalo, MD – Pediatric Endocrine Society (pedsendo.org)
Historical Tidbit: Friedrich Wöhler (July 31, 1800 to September 3, 1882) and the Synthesis of Urea
Submitted by Alan Rogol, MD
ICCBH 2024, The 11th International Conference on Children’s Bone Health
The International Society for Children’s Bone Health will be held in the beautiful, musical city of Salzburg, Austria from Saturday 22 to Tuesday 25 June 2024, https://theiscbh.org/iccbh/
Scientists, clinicians, trainees, allied health professionals and others will meet to better understand childhood bone health and disease, recent developments in clinical outcomes, novel therapies, and genetic discoveries.
Please submit your abstracts! The abstract deadline is Monday 5th February 2024. https://theiscbh.org/iccbh/iccbh-2024-abstracts/
ICCBH 2024 is your opportunity to hear about and discuss the newest developments in our understanding of paediatric bone health.
We look forward to seeing you in Salzburg in June!