About Us:
Rhythm Pharmaceuticals is a global commercial-stage biopharmaceutical company focused on transforming the lives of patients and their families living with rare neuroendocrine diseases caused by impairment in the melanocortin-4 receptor (MC4R) pathway by rapidly advancing care and precision medicines addressing the root cause. To learn more, please visit https://hcp.rhythmtx.com/.
Rhythm has commercialized IMCIVREE (setmelanotide). For more information about IMCIVREE, including prescribing and safety information, visit https://www.IMCIVREE.com.
Rhythm continues to advance its clinical research program in other rare MC4R pathway diseases, with multiple ongoing and planned Phase 2 and Phase 3 clinical trials in acquired hypothalamic obesity resulting from injury to hypothalamus and MC4R pathway diseases due to other genetic variants. For more details on our comprehensive clinical development program, please visit https://www.rhythmtx.com/clinical-trials/.
In addition to clinical trials, Rhythm continues to be a leader in understanding rare MC4R pathway diseases. Rhythm has developed the Uncovering Rare Obesity Program, which provides no-cost, extensive genetic testing to support diagnosis of rare MC4R pathway diseases. Rhythm is building the largest database of DNA sequences from individuals living with severe obesity to improve the understanding of MC4R pathway diseases.
Address:
222 Berkeley Street
12th Floor
Boston, MA 02116
United States
Phone:
(857) 264-4280
Email:
medinfo@rhythmtx.com
Website:
Brief summary of the
materials and/or video content:
1. Rare Melanocortin-4 Receptor (MC4R) Pathway Diseases (Mechanism of Disease Video)
The MC4R pathway in the hypothalamus is a key signaling pathway responsible for regulating hunger, food intake, and energy expenditure, which consequently affects body weight. Learn more about this pathway in the Rare MC4R Pathway Diseases – Mechanism of Disease Video.
2. Bardet-Biedl Syndrome Diagnosis Tool
A brochure that discusses diagnosing Bardet-Biedl Syndrome. Includes information on the clinical features and manifestations of the disease and discusses the variability of clinical presentations.
3. BBS Diagnosis HCP Educational Video
A short video that discusses diagnosing Bardet-Biedl Syndrome. Includes information on the clinical features and manifestations of the disease and discusses the variability of clinical presentations.
4. Hyperphagia Questionnaire
Hyperphagia Questionnaire that can be used to assess the presence of symptoms and behaviors of hyperphagia in patients.
5. Gene Frequency Handout
A handout with information about the frequency of obesity-associated gene variants as identified in our Uncovering Rare Obesity program.
6. IMCIVREE What to Expect (POMC, PCSK1, LEPR Deficiency)
A brochure with information about what to expect when starting IMCIVREE for patients with POMC, PCSK1, or LEPR deficiency.
7. IMCIVREE What to Expect (Bardet-Biedl Syndrome)
A brochure with information about what to expect when starting IMCIVREE for patients with Bardet-Biedl Syndrome.
8. IMCIVREE PI
Please see the most up-to-date Prescribing Information for IMCIVREE
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