Hyperglycemic Hyperosmolar Syndrome in Children: Pathophysiological Considerations and Suggested Guidelines for Treatment (J of Pediatrics 2011)

HHS pathophysiology, treatment and complications in children.

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Continuous Subcutaneous Insulin Infusion in Very Young Children With Type 1 Diabetes. PES D&T Committee Position statement. (Pediatrics 2006)

This review summarizes efficacy and safety of continuous subcutaneous insulin infusion in children ≤6 years of age, present potential pros and cons of using insulin pumps…

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Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

Prospective study conducted by the Diabetes Prevention Program Research Group, looking at reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

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ESPE/PES Consensus Statement on DKA in Children and Adolescents (Pediatrics 2004)

There is debate as to whether physicians treating DKA can prevent or predict the occurrence of cerebral edema and the appropriate site(s) for children with DKA…

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Risk Factors for Cerebral Edema in Children With Diabetic Ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics (NEJM 2001)

A Multi-Center Study in 61 Children to Identify Risk Factors for Cerebral Edema in Diabetic Ketoacidosis, presented by the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics

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The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus (DCCT)

DCCT research group results on effect of intensive treatment on complications.

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Historic Value: Pancreatic Extracts in the Treatment of Diabetes Mellitus

Iconic paper by Banting and Best describing use of insulin in diabetes for the first time.

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