November 30, 2020
How to Apply
Submit an application online and provide two letters of support. For more detailed instructions, see award description.
Please see the separate application link for 2nd year submission instructions.
Application Deadline: November 30, 2020 at 5:00pm
To promote early career research development of academic pediatric endocrinologists.
Qualifications of Candidate
Senior fellows or early stage faculty members who are PES members in good standing are eligible to apply for the Clinical Scholar Award. Applicants must provide institutional documentation of junior faculty status at the planned time of the award with the additional stipulations as noted below. US citizenship or green card status is NOT required. Those with career plans in North America are favored.
A candidate may apply for support if he or she:
- Is in the final year of training as an endocrinology fellow or is within the first 3 years of a full-time junior faculty position in Pediatric Endocrinology.
- Has either an MD or DO degree.
- Has completed a minimum of 2 years of pediatric endocrinology fellowship training.
- Has a faculty rank that is no higher than Assistant Professor.
- Does not have K12, K23, or K08 funding and is not a PI on an R21, R01, or NSF at the time of grant award period.
Should the candidate have other forms of extramural research support, they must submit their hypotheses and budget to identify potential overlaps in funding.
Note that multiple applications from one institution may be submitted, but only one application will be funded from a single institution.
Awardees will be expected to present their research findings at an oral plenary session at the national PES meeting at the conclusion of the granting period. PES will also request that awardees indicate acknowledgement of funding from PES and provide copies of all manuscripts generated from work supported by the PES grant as well as information about awardees’ future academic appointments and subsequent grant awards for 5 years following completion of the PES award.
Amount of Award
The award is up to $50,000 for one year. The exact amount of funding for each review cycle will be determined by the Awards Committee depending on the amount of available funds at the time of review of the application. Funding for a second year will be based on submission of a progress report and the competitive renewal of the proposal.
Awardees are requested to notify the committee of any delays in the progress of their proposal. For funds that are not used during the term of the grant award, a one-time request for a no-cost extension (NCE) can be made to the Awards Committee and Board of Directors of PES, and, if approved, a 1-year NCE will be granted.
Support from the Clinical Scholar award is only for research-related expenses and research career development, including technical support. The Sponsor must verify salary support for the Scholar. The funds shall not be used for the salary of the awardee, and institutions may not use more than 5% of the grant award for indirect or overhead expenses. Concomitant funding for the project from other grants is permitted.
However, if a candidate holds or is applying for any other grant proposing studies related to those in the CSA, PES requests that a copy of the specific aims, hypotheses, and budget of the other grant(s) be included in the CSA application so that reviewers can assess the degree of potential overlap.
Detailed Application Instructions
Applications are submitted on-line through the PES website. An applicant must be a member of PES (dues paid for this current year) to be able to access the application. Applicants will then be directed to register. This will allow initiation of the application process and enable returning to finish different sections at a later time using the registration log-in.
The Career Training and Research sections (parts 3 and 4 under the Applicant Section) must be limited to no more than seven pages in Arial 11-point or comparable font. An application not compliant with these guidelines or received after the due date will be returned to the applicant and not reviewed. Applications must contain a Career Development Plan, an Individual Development Plan, a Research Plan, and a detailed Budget. The Career Development Plan must justify the need for the requested period of support, be tailored to the prior research experience and career development needs of the candidate, and be designed to move the candidate from the mentored phase to the independent phase of his/her research career over about 5 years. The Individual Development Plan is a description of the skills and competencies that are to be achieved, the development activities with which the competencies will be achieved, and a timetable for execution of these competencies. The Research Plan must have intrinsic research importance as well as serve as a suitable vehicle for learning the theories, methodologies, and conceptualizations necessary to become an independent investigator. If the application contains the use of human subjects or animals, documentation of the Human Subjects or IACUC approval must be provided before an award can be made to the institution.
Two letters of support are required and should be submitted with the application. One must be from the Division Chief (Sponsor) and the other from the Research Mentor (individual supervising the research project) who is an established investigator with a record of current extramural support as evidenced on his or her NIH Biosketch. If the Division Chief and Research Mentor are the same person, a letter from the Department Chair is required. Additionally, applicants must establish an appropriate mentoring committee and provide the names and qualifications of these committee members.
General Scoring of Applications
Applications will be reviewed by the PES Awards Committee, as well as by expert external reviewers. Reviewers will use the NIH grant application 9-point scale scoring system for the Overall Impact Score and Individual Scores for five core criteria:
2019 - 2020
Daniel Zeve – Reprogramming Gastrointestinal Stem Cells into Endocrine Cells
Despoina Manousaki - Identifying clinically-relevant circulating protein biomarkers for type 1 diabetes
2018 - 2019
Miranda Broadney, MD, MPH - Break It Up: A study evaluating the effects of interrupting daily sedentary behavior in youth on glucose tolerance and lipid metabolism
Amanda Ackerman, MD, PhD - Identifying Targets to Enhance β Cell Response in Diabetes Using Single-Cell Functional Genomics
Shylaja Srinivasan, MD - Understanding the Genetic Determinants of Weight Loss in Response to Therapeutic Interventions for Type 2 Diabetes in Adults and Children
Stephanie Roberts - Transgenic Expression of Mkrn3 in the Arcuate Nucleus of the Hypothalamus: Impact on the Neuroendocrine Control of Puberty and Reproduction
2017 - 2018
Charumathi Baskaran - Role of gonadal hormones in regulation of anxiety and depression in athletes
Shanlee Davis - Energy metabolism in boys with Klinefelter Syndrome
Christine Ferrara - Genetic variants of lipid metabolism and the effect on beta-cell function in type 1 diabetes
2016 - 2017
Shylaja Srinivasan, MD - Genetics of type 2 diabetes and related therapeutic strategies in youth
Youn Hee Jee, MD - The role of PSD-93 in the initiation of puberty and in the etiology of pubertal delay
Stephanie Roberts, MD - Transgenic expression of Mkrn3 in the arcuate nucleus of the hypothalamus: impact on the neuroendocrine control of puberty and reproduction
2015 - 2016
Jeffrey Roizen, MD, PhD - CYP2R1, the Vitamin D 25-hydroxylase, a critical mechanistic link between disease and serum 25(OH)D
Emily Sims, MD - β cell Derived miR-21 as an Intrinsic Protective Response and Biomarker in Type 1 Diabetes
Diana Stanescu, MD - The maturation of pancreatic endocrine cells in human development
Stephanie Sisley, MD - Mechanisms of CNS Vitamin D in weight regulation
2014 - 2015
Shana McCormack, MD - Translational investigation of abnormal fat metabolism in mitochondrial disease
Jennifer Todd, MD - Genetic association studies of diabetic nephropathy
2013 - 2015
Janet Crane, MD - Temporal-spatial regulation of differentiation of mesenchymal stem cells by Insulin-like growth factor Type 1 and relationship to peak bone mass acquisition
Lily Chao, MD - Nur77 – a novel regulator of muscle growth
Andrew Dauber M.D. - Rare genetic variants as novel causes of short stature
Natalie Shaw, M.D. - The interaction between sleep and reproductive hormone secretion during puberty
Yee-Ming Chan, M.D., PhD - Using kisspeptin to interrogate the human GnRH network
Mark DeBoer, M.D. - Improving endocrine-related outcomes in pre-pubertal colitis
Elvira Isganaitis, M.D. - Obesity and diabetes risk following prenatal undernutrition: identifying molecular mechanisms and targeted therapies
Nancie J. MacIver, M.D. - Leptin as a regulator of T cell metabolism and function
Jennifer Yee, M.D. - Effect of SCD1 Inhibition on adipocyte differentiation in newborn rats programmed to develop adult obesity
Clement Cheung, M.D., Ph.D. - A novel transcriptional factor in VMH development and physiology
Scott Blackman, M.D. - Genetic modifiers of diabetes in cystic fibrosis
Maureen Su, M.D. - The Role of central tolerance in autoimmune endocrinopathies
Sara DiVall, M.D. - Growth factor regulation of the GnRH neuron
Brian Feldman, M.D. - Role of the glucocorticoid receptor in adipogenesis and implications for diabetes and metabolism
Amy Fleischman, M.D. - Mitochondrial function and insulin resistance in obese and lean children
Dennis Chia, M.D.
Michael Haller, M.D.
Sudha Biddinger, M.D.
Sheela Natash Magge, M.D.
Kuk-Wha Lee, M.D., Ph.D.
Bradley S. Miller, M.D., Ph.D.
Jennifer L. Miller, M.D.
Radhika Muzumdar, M.D.
David T. Breault, M.D., Ph.D.
Robert J. Ferry, Jr., M.D.
Andrea M. Haqq, M.D.
Jake A. Kushner, M.D.
Kathleen Bethin, M.D.
David Geller, M.D., Ph.D.
Andrea Kelly, M.D.
Anna Spagnoli, M.D.
Atul Butte, M.D.
Rubina Heptulla, M.D.
Stephen Huang, M.D.
Daniel Marks, M.D., Ph.D.
Adda Grimberg, M.D.
Mark R. Palmert, M.D., Ph.D.
Pamela M. Thomas, M.D.
Ruben Diaz, M.D., Ph.D.
Michael P. Wajnrajch, M.D., Ph.D.
Jon M. Nakamoto, M.D., Ph.D.
Cheri L. Deal, M.D., Ph.D.
Patricia Y. Fechner, M.D.
Stephen E. Gitelman, M.D.
Charmian A. Quigley, M.D.
Paul M. Martha, Jr., M.D.
Scott A. Rivkees, M.D.
Nancy J. Charest, M.D.
Samuel J. Casella, M.D.